Interactor 1: TAP2 (P36372)
Antigen peptide transporter 2 (APT2) (EC 7.4.2.14) (ATP-binding cassette sub-family B member 3)
Gene: TAP2

Interactor 2: P97949 (P97949)
ABC-type antigen peptide transporter (EC 7.4.2.14)
Gene: Tap1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 10508608, 12047747
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ABC_membrane~ABC_membrane, ABC_membrane~ABC_tran, ABC_tran~ABC_tran
Common GO terms GO:0005524 - ATP binding
GO:0015433 - ABC-type peptide antigen transporter activity
GO:0016887 - ATP hydrolysis activity
GO:0019885 - antigen processing and presentation of endogenous peptide antigen via MHC class I
GO:0023029 - MHC class Ib protein binding
and 6 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 703
Rn

1 725
+ Rn
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Mm
+ Hs
+ Ce
+ Vc
+ Ec
+ At
+ Ec
+ Hs

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Last updated: 15 Jul 2024