Interactor 1: TRI23 (P36406)
E3 ubiquitin-protein ligase TRIM23 (EC 2.3.2.27) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING finger protein 46) (RING-type E3 ubiquitin transferase TRIM23) (Tripartite motif-containing protein 23)
Gene: TRIM23

Interactor 2: GEM (P55040)
GTP-binding protein GEM (GTP-binding mitogen-induced T-cell protein) (RAS-like protein KIR)
Gene: GEM

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.720

The method score is based on:

Property Details
Experiments 16189514, 32296183, 19060904, unassigned1304, 31515488
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005634 - nucleus
GO:0005886 - plasma membrane
GO:0019003 - GDP binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 574
Hs

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Last updated: 15 Jul 2024