HitPredict

Interactor 1: TRI23 (P36406)
E3 ubiquitin-protein ligase TRIM23 (EC 2.3.2.27) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING finger protein 46) (RING-type E3 ubiquitin transferase TRIM23) (Tripartite motif-containing protein 23)
Gene: TRIM23

Interactor 2: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	28681414
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 574 Hs			1 152
+	Hs
		734819 TRI23_HUMAN (1-574): 1.73e-139: 418: 100.00		UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89
+	Hs
		734563 TRI23_HUMAN (1-574): 1.73e-139: 418: 100.00		UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21
+	Hs
		734581 TRI23_HUMAN (1-574): 1.73e-139: 418: 100.00		UB2D2_HUMAN (4-149): 9.96e-80: 233: 46.58
+	Hs
		734570 TRI23_HUMAN (1-574): 1.73e-139: 418: 100.00		UB2D3_HUMAN (4-149): 1.46e-78: 230: 45.89
+	Hs
		734733 TRI23_HUMAN (1-574): 1.73e-139: 418: 100.00		UB2E2_HUMAN (1-149): 1.52e-75: 225: 44.97
+	Hs
		734564 TRI23_HUMAN (1-574): 1.73e-139: 418: 100.00		UB2E1_HUMAN (1-149): 1.93e-73: 219: 45.64
+	Hs
		895769 ARF6_HUMAN (399-567): 3.05e-87: 269: 54.44		UB2D3_HUMAN (4-149): 1.46e-78: 230: 45.89
+	Hs
		1356055 TRIM1_HUMAN (21-400): 5.38e-69: 238: 19.51		UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89
+	Hs
		1151762 Q6GX22_HUMAN (23-400): 6.72e-69: 237: 19.60		UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89
+	Hs
		849480 TRIM1_HUMAN (21-400): 5.38e-69: 238: 19.51		UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21
+	Hs
		919896 TRIM1_HUMAN (21-400): 5.38e-69: 238: 19.51		UB2D2_HUMAN (4-149): 9.96e-80: 233: 46.58
+	Hs
		895945 TRIM1_HUMAN (21-400): 5.38e-69: 238: 19.51		UB2D3_HUMAN (4-149): 1.46e-78: 230: 45.89
+	Hs
		1297378 TRIM1_HUMAN (21-400): 5.38e-69: 238: 19.51		UB2E2_HUMAN (1-149): 1.52e-75: 225: 44.97
+	Hs
		1282363 TRIM1_HUMAN (21-400): 5.38e-69: 238: 19.51		UB2E3_HUMAN (1-149): 3.17e-75: 224: 44.97
+	Hs
		851905 TRIM1_HUMAN (21-400): 5.38e-69: 238: 19.51		UB2E1_HUMAN (1-149): 1.93e-73: 219: 45.64
+	Hs
		896562 TRIM1_HUMAN (21-400): 5.38e-69: 238: 19.51		UBE2N_HUMAN (1-152): 1.51e-73: 218: 100.00
+	Hs
		896464 Q6GX22_HUMAN (23-400): 6.72e-69: 237: 19.60		UBE2N_HUMAN (1-152): 1.51e-73: 218: 100.00