HitPredict

Interactor 1: TRI23 (P36406)
E3 ubiquitin-protein ligase TRIM23 (EC 2.3.2.27) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING finger protein 46) (RING-type E3 ubiquitin transferase TRIM23) (Tripartite motif-containing protein 23)
Gene: TRIM23

Interactor 2: Q0P6H7 (Q0P6H7)
TRIM29 protein
Gene: TRIM29

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	zf-B_box~zf-B_box, zf-B_box~zf-RING_UBOX
Common GO terms	GO:0008270 - zinc ion binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 574 Hs			1 446
+	Hs
		734625 TRI23_HUMAN (1-574): 1.73e-139: 418: 100.00		TRI29_HUMAN (1-446): 1.68e-152: 446: 99.10
+	Hs
		734764 TRI23_HUMAN (1-574): 1.73e-139: 418: 100.00		TRIM6_HUMAN (7-384): 1.03e-83: 267: 19.21
+	Hs
		1048816 TRIM1_HUMAN (21-400): 5.38e-69: 238: 19.51		TRI29_HUMAN (1-446): 1.68e-152: 446: 99.10
+	Hs
		536745 TRI23_HUMAN (1-574): 1.73e-139: 418: 100.00		TRI27_HUMAN (4-411): 1.83e-71: 235: 15.90
+	Hs
		734763 TRI23_HUMAN (1-574): 1.73e-139: 418: 100.00		TRI31_HUMAN (7-331): 4.55e-60: 203: 15.47
+	Hs
		537123 TRIM1_HUMAN (21-400): 5.38e-69: 238: 19.51		TRI27_HUMAN (4-411): 1.83e-71: 235: 15.90
+	Hs
		918939 RAB1A_HUMAN (397-569): 2.41e-61: 203: 15.17		TRIM6_HUMAN (7-384): 1.03e-83: 267: 19.21
+	Hs
		1356047 TRIM1_HUMAN (21-400): 5.38e-69: 238: 19.51		TRIM1_HUMAN (3-247): 6.25e-52: 188: 21.18
+	Hs
		175727 TRIM1_HUMAN (21-400): 5.38e-69: 238: 19.51		TRI18_HUMAN (3-276): 1.46e-51: 186: 21.83
+	Hs
		1261128 TRIM1_HUMAN (21-400): 5.38e-69: 238: 19.51		TRI41_HUMAN (40-251): 3.09e-46: 171: 22.97