HitPredict

Interactor 1: TRI23 (P36406)
E3 ubiquitin-protein ligase TRIM23 (EC 2.3.2.27) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING finger protein 46) (RING-type E3 ubiquitin transferase TRIM23) (Tripartite motif-containing protein 23)
Gene: TRIM23

Interactor 2: TRI55 (Q9BYV6)
Tripartite motif-containing protein 55 (EC 2.3.2.27) (Muscle-specific RING finger protein 2) (MuRF-2) (MuRF2) (RING finger protein 29)
Gene: TRIM55

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.793

The method score is based on:

Property Details
Experiments 31391242, 22493164
Identification Methods two hybrid, two hybrid prey pooling approach, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-B_box~zf-B_box, zf-B_box~zf-RING_UBOX, zf-RING_UBOX~zf-RING_UBOX
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0008270 - zinc ion binding
GO:0016567 - protein ubiquitination
GO:0061630 - ubiquitin protein ligase activity
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 574
Hs

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Last updated: 15 Jul 2024