HitPredict

Interactor 1: TRI23 (P36407)
E3 ubiquitin-protein ligase TRIM23 (EC 2.3.2.27) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING-type E3 ubiquitin transferase TRIM23) (Tripartite motif-containing protein 23)
Gene: Trim23

Interactor 2: UBC (Q63429)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]
Gene: UBC

Species: Rattus norvegicus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22871113
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-RING_UBOX
Common GO terms	GO:0005634 - nucleus GO:0016567 - protein ubiquitination
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 573 Rn			1 810
+	Rn
		102473 G3V6H0_RAT (396-568): 3.9e-56: 189: 14.61		UBC_RAT (1-810): 0: 1000: 100.00
+	Rn
		936845 RAB8B_RAT (396-567): 1.64e-55: 187: 20.90		UBC_RAT (1-810): 0: 1000: 100.00
+	Hs
		475423 TRI23_HUMAN (1-573): 1.97e-131: 397: 96.86		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		476427 TRI36_HUMAN (20-380): 2.33e-84: 279: 21.85		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		475624 ARF1_HUMAN (399-568): 2.43e-68: 220: 60.59		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		475328 RO52_HUMAN (17-385): 1.37e-55: 196: 14.36		UBC_HUMAN (1-533): 0: 662: 99.81
+	Dr
		91588 E7F1U3_DANRE (4-424): 1.32e-55: 202: 17.76		F1QHN6_DANRE (305-801): 0: 602: 96.18
+	Sc
		350834 YPT1_YEAST (396-571): 2.6e-55: 187: 17.13		UBI4P_YEAST (457-801): 3.68e-132: 400: 90.73
+	At
		483049 ARF2B_ARATH (386-568): 1.97e-69: 223: 56.83		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	At
		1092212 Q9LYJ3_ARATH (386-565): 5.58e-69: 222: 58.33		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	At
		1092235 Q9M1P5_ARATH (386-568): 3.29e-69: 222: 56.83		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	Hs
		734585 TRI23_HUMAN (1-573): 1.97e-131: 397: 96.86		RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00
+	At
		656930 RAD2A_ARATH (396-573): 2.76e-58: 195: 16.94		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	At
		734432 ARF1_ARATH (401-568): 3.13e-57: 191: 60.71		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	At
		1091637 RAB1B_ARATH (398-567): 2.81e-56: 190: 18.29		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	Hs
		475200 TRI36_HUMAN (20-380): 2.33e-84: 279: 21.85		UBB_HUMAN (1-77): 1.17e-26: 110: 98.70
+	Hs
		923954 ARF5_HUMAN (389-567): 4.14e-67: 217: 54.19		RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00
+	Hs
		397768 ARF4_HUMAN (386-567): 5.05e-68: 219: 54.40		ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69