Interactor 1: MP2K2 (P36507)
Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)
Gene: MAP2K2

Interactor 2: MP2K2 (P36507)
Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)
Gene: MAP2K2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.829

The method score is based on:

Property Details
Experiments 31980649, 8226933, 11909642
Identification Methods affinity chromatography technology, enzymatic study, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000165 - MAPK cascade
GO:0004674 - protein serine/threonine kinase activity
GO:0004708 - MAP kinase kinase activity
GO:0004712 - protein serine/threonine/tyrosine kinase activity
GO:0004713 - protein tyrosine kinase activity
and 42 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 400
Hs

1 400
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+ Dm
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Last updated: 15 Jul 2024