HitPredict

Interactor 1: MP2K2 (P36507)
Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)
Gene: MAP2K2

Interactor 2: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.628

The method score is based on:

Property Details
Experiments 35271311, 32707033
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000165 - MAPK cascade
GO:0005634 - nucleus
GO:0005783 - endoplasmic reticulum
GO:0005829 - cytosol
GO:0005925 - focal adhesion
and 1 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 400
Hs

1 255
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Last updated: 15 Jul 2024