Interactor 1: MP2K2 (P36507)
Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)
Gene: MAP2K2
Interactor 2: KSR1 (Q8IVT5)
Kinase suppressor of Ras 1 (EC 2.7.11.1)
Gene: KSR1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.84 | 1.00 | 0.918 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31980649, 35271311, 32707033, 11909642, unassigned2173 |
| Identification Methods | affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, pull down |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PK_Tyr_Ser-Thr~Pkinase |
| Common GO terms | GO:0004674 - protein serine/threonine kinase activity GO:0005078 - MAP-kinase scaffold activity GO:0005524 - ATP binding GO:0005783 - endoplasmic reticulum GO:0005829 - cytosol and 2 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
