HitPredict

Interactor 1: MP2K2 (P36507)
Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)
Gene: MAP2K2

Interactor 2: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.620

The method score is based on:

Property Details
Experiments 20936779, 18624398
Identification Methods two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0046872 - metal ion binding
GO:0048471 - perinuclear region of cytoplasm
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 400
Hs

1 334
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024