HitPredict

Interactor 1: MP2K2 (P36507)
Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)
Gene: MAP2K2

Interactor 2: WDR83 (Q9BRX9)
WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1)
Gene: WDR83

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	15118098
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 400 Hs			1 315
+	Hs
		972247 MP2K1_HUMAN (2-399): 2.32e-128: 376: 78.14		WDR83_HUMAN (1-315): 2.96e-102: 303: 100.00
+	Hs
		625202 CDK2_HUMAN (69-375): 3.95e-124: 362: 25.16		LIS1_HUMAN (63-312): 8.99e-76: 239: 19.78
+	Hs
		972235 MP2K1_HUMAN (2-399): 2.32e-128: 376: 78.14		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	At
		1105322 KIN10_ARATH (71-352): 3.12e-128: 380: 21.88		PRL1_ARATH (103-312): 2.25e-55: 188: 23.72
+	Hs
		681967 AKT1_HUMAN (43-351): 3.37e-124: 369: 20.12		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Hs
		414806 CDK1_HUMAN (69-375): 8.1e-111: 328: 24.76		LIS1_HUMAN (63-312): 8.99e-76: 239: 19.78
+	Hs
		625543 CDK2_HUMAN (69-375): 3.95e-124: 362: 25.16		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	At
		955193 KIN11_ARATH (71-344): 2.46e-124: 370: 24.10		PRL1_ARATH (103-312): 2.25e-55: 188: 23.72
+	Hs
		734902 MP2K2_HUMAN (1-400): 1.09e-125: 370: 100.00		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Hs
		1027412 STK3_HUMAN (54-390): 1.33e-108: 329: 30.37		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Hs
		415016 CDK1_HUMAN (69-375): 8.1e-111: 328: 24.76		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Sc
		565470 PHO85_YEAST (68-372): 5.74e-110: 326: 25.40		NLE1_YEAST (2-94): 1.96e-23: 101: 30.11