Interactor 1: VATE1 (P36543)
V-type proton ATPase subunit E 1 (V-ATPase subunit E 1) (V-ATPase 31 kDa subunit) (p31) (Vacuolar proton pump subunit E 1)
Gene: ATP6V1E1

Interactor 2: VPP2 (Q9Y487)
V-type proton ATPase 116 kDa subunit a 2 (V-ATPase 116 kDa subunit a 2) (Lysosomal H(+)-transporting ATPase V0 subunit a 2) (TJ6) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2)
Gene: ATP6V0A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains V_ATPase_I~vATP-synt_E
Common GO terms GO:0005765 - lysosomal membrane
GO:0016241 - regulation of macroautophagy
GO:0046961 - proton-transporting ATPase activity, rotational mechanism
GO:0051117 - ATPase binding
GO:1902600 - proton transmembrane transport
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 226
Hs

1 856
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc

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Last updated: 15 Jul 2024