HitPredict

Interactor 1: RL4 (P36578)
Large ribosomal subunit protein uL4 (60S ribosomal protein L1) (60S ribosomal protein L4)
Gene: RPL4

Interactor 2: GNL3 (Q9BVP2)
Guanine nucleotide-binding protein-like 3 (E2-induced gene 3 protein) (Novel nucleolar protein 47) (NNP47) (Nucleolar GTP-binding protein 3) (Nucleostemin)
Gene: GNL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 34349018
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005730 - nucleolus GO:0016020 - membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 427 Hs			1 549
+	Hs
		736451 RL4_HUMAN (1-427): 0: 609: 100.00		NOG2_HUMAN (8-492): 4.75e-113: 354: 24.80
+	Hs
		736279 RL4_HUMAN (1-427): 0: 609: 100.00		GNL1_HUMAN (23-422): 1.68e-91: 294: 18.50
+	Hs
		736718 RL4_HUMAN (1-427): 0: 609: 100.00		LSG1_HUMAN (50-256): 5.15e-48: 178: 22.12
+	Sc
		499004 RL4A_YEAST (4-335): 9.67e-150: 431: 60.18		LSG1_YEAST (70-497): 7.39e-107: 335: 17.16
+	Sc
		829636 RL4B_YEAST (4-335): 1.82e-149: 430: 60.18		LSG1_YEAST (70-497): 7.39e-107: 335: 17.16
+	Sc
		499018 RL4A_YEAST (4-335): 9.67e-150: 431: 60.18		NOG2_YEAST (6-404): 1.52e-105: 327: 28.22
+	Sc
		829650 RL4B_YEAST (4-335): 1.82e-149: 430: 60.18		NOG2_YEAST (6-404): 1.52e-105: 327: 28.22
+	Sc
		498944 RL4A_YEAST (4-335): 9.67e-150: 431: 60.18		NUG1_YEAST (7-449): 3.13e-93: 296: 27.15
+	Sc
		766661 RL4B_YEAST (4-335): 1.82e-149: 430: 60.18		NUG1_YEAST (7-449): 3.13e-93: 296: 27.15