HitPredict

Interactor 1: PCK1 (P36582)
Protein kinase C-like 1 (EC 2.7.11.13)
Gene: PCK1

Interactor 2: RHO2 (Q10133)
GTP-binding protein rho2
Gene: RHO2

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	10504305
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1_1~Ras, HR1~Ras, Pkinase~Ras
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0032153 - cell division site
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 988 Sp			1 200
+	Sp
		736856 PCK1_SCHPO (1-988): 0: 895: 100.00		RHO5_SCHPO (7-199): 1.85e-90: 265: 53.06
+	Sp
		736851 PCK1_SCHPO (1-988): 0: 895: 100.00		RHO1_SCHPO (1-199): 1.12e-83: 248: 55.88
+	Sp
		736850 PCK1_SCHPO (1-988): 0: 895: 100.00		CDC42_SCHPO (7-199): 1.8e-76: 229: 44.56
+	Sp
		736855 PCK1_SCHPO (1-988): 0: 895: 100.00		RHO4_SCHPO (9-177): 8.63e-59: 184: 53.80
+	Sp
		736865 PCK2_SCHPO (1-984): 0: 802: 45.38		RHO5_SCHPO (7-199): 1.85e-90: 265: 53.06
+	Sp
		736860 PCK2_SCHPO (1-984): 0: 802: 45.38		RHO2_SCHPO (1-200): 5.27e-85: 251: 100.00
+	Sp
		736859 PCK2_SCHPO (1-984): 0: 802: 45.38		RHO1_SCHPO (1-199): 1.12e-83: 248: 55.88
+	Sp
		736857 PCK2_SCHPO (1-984): 0: 802: 45.38		CDC42_SCHPO (7-199): 1.8e-76: 229: 44.56
+	Sp
		736864 PCK2_SCHPO (1-984): 0: 802: 45.38		RHO4_SCHPO (9-177): 8.63e-59: 184: 53.80
+	Hs
		915706 PKN2_HUMAN (2-987): 0: 649: 23.33		RHOB_HUMAN (7-197): 1.16e-91: 268: 57.07
+	Hs
		436326 PKN2_HUMAN (2-987): 0: 649: 23.33		RHOC_HUMAN (10-199): 2.12e-83: 246: 56.32
+	Hs
		894056 PKN2_HUMAN (2-987): 0: 649: 23.33		CDC42_HUMAN (9-199): 4.58e-82: 243: 47.12
+	Hs
		925308 PKN2_HUMAN (2-987): 0: 649: 23.33		RAC1_HUMAN (9-199): 1.38e-79: 237: 48.69
+	Hs
		545401 PKN2_HUMAN (2-987): 0: 649: 23.33		RAC2_HUMAN (9-199): 4.91e-76: 228: 45.55
+	Hs
		900514 PKN2_HUMAN (2-987): 0: 649: 23.33		RHOA_HUMAN (10-199): 4.08e-76: 228: 57.90
+	Hs
		951021 PKN2_HUMAN (2-987): 0: 649: 23.33		RHOG_HUMAN (8-199): 8.49e-76: 227: 46.35
+	Hs
		681775 AKT1_HUMAN (531-987): 2.71e-154: 466: 37.20		RAC1_HUMAN (9-199): 1.38e-79: 237: 48.69
+	Sc
		419673 KPC1_YEAST (598-988): 1.8e-133: 432: 54.22		RHO1_YEAST (1-189): 2.77e-90: 265: 59.69
+	Dm
		52723 PKN_DROME (659-986): 8.97e-99: 338: 52.12		RAC1_DROME (9-199): 3.56e-77: 231: 47.12
+	Dm
		52724 PKN_DROME (659-986): 8.97e-99: 338: 52.12		RHO1_DROME (10-199): 1.22e-74: 224: 56.32