HitPredict

Interactor 1: PCK2 (P36583)
Protein kinase C-like 2 (EC 2.7.11.13)
Gene: PCK2

Interactor 2: RHO5 (Q9HE04)
GTP-binding protein rho5
Gene: RHO5

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	25651781
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1_1~Ras, HR1~Ras, Pkinase~Ras
Common GO terms	GO:0005634 - nucleus GO:0032153 - cell division site GO:0051286 - cell tip
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1016 Sp			1 200
+	Sp
		736859 PCK2_SCHPO (1-1016): 0: 884: 100.00		RHO1_SCHPO (1-200): 3.42e-80: 239: 85.64
+	Sp
		736857 PCK2_SCHPO (1-1016): 0: 884: 100.00		CDC42_SCHPO (1-200): 2.18e-78: 234: 48.50
+	Sp
		736860 PCK2_SCHPO (1-1016): 0: 884: 100.00		RHO2_SCHPO (5-180): 2.89e-76: 229: 56.82
+	Sp
		736864 PCK2_SCHPO (1-1016): 0: 884: 100.00		RHO4_SCHPO (3-175): 2.08e-74: 224: 61.71
+	Sp
		736851 PCK1_SCHPO (1-1002): 0: 743: 45.40		RHO1_SCHPO (1-200): 3.42e-80: 239: 85.64
+	Sp
		736856 PCK1_SCHPO (1-1002): 0: 743: 45.40		RHO5_SCHPO (1-200): 3.5e-80: 238: 100.00
+	Sp
		736850 PCK1_SCHPO (1-1002): 0: 743: 45.40		CDC42_SCHPO (1-200): 2.18e-78: 234: 48.50
+	Sp
		736852 PCK1_SCHPO (1-1002): 0: 743: 45.40		RHO2_SCHPO (5-180): 2.89e-76: 229: 56.82
+	Sp
		736855 PCK1_SCHPO (1-1002): 0: 743: 45.40		RHO4_SCHPO (3-175): 2.08e-74: 224: 61.71
+	Hs
		915625 KPCD_HUMAN (273-1009): 0: 558: 25.88		RHOB_HUMAN (5-183): 8.33e-93: 270: 67.60
+	Rn
		448411 KPCD_RAT (273-1009): 0: 560: 26.01		RAC1_RAT (7-200): 4.35e-83: 246: 54.64
+	Hs
		900406 KPCD_HUMAN (273-1009): 0: 558: 25.88		RHOA_HUMAN (1-200): 8.79e-81: 240: 64.00
+	Dm
		52723 PKN_DROME (12-1006): 4.63e-180: 557: 25.42		RAC1_DROME (7-200): 4.68e-80: 238: 53.09
+	Hs
		436269 KPCD_HUMAN (273-1009): 0: 558: 25.88		RHOC_HUMAN (1-200): 1.11e-78: 235: 63.00
+	Dm
		52724 PKN_DROME (12-1006): 4.63e-180: 557: 25.42		RHO1_DROME (1-200): 4.2e-78: 233: 67.00
+	Hs
		925778 M3K4_HUMAN (5-949): 1.09e-166: 532: 12.85		RAC1_HUMAN (7-200): 4.35e-83: 246: 54.64
+	Hs
		894645 M3K4_HUMAN (5-949): 1.09e-166: 532: 12.85		CDC42_HUMAN (6-200): 1.39e-78: 234: 51.80
+	Hs
		545401 PKN2_HUMAN (112-1006): 3.79e-170: 525: 24.54		RAC2_HUMAN (7-200): 2.07e-79: 236: 52.06
+	Hs
		436326 PKN2_HUMAN (112-1006): 3.79e-170: 525: 24.54		RHOC_HUMAN (1-200): 1.11e-78: 235: 63.00
+	Hs
		120458 PKN2_HUMAN (112-1006): 3.79e-170: 525: 24.54		RHOD_HUMAN (8-180): 4.29e-71: 216: 52.02