HitPredict

Interactor 1: RPB1 (P36594)
DNA-directed RNA polymerase II subunit rpb1 (RNA polymerase II subunit 1) (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase III largest subunit)
Gene: RPB1

Interactor 2: RPB3 (P37382)
DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3) (RNA polymerase II subunit B3) (DNA-directed RNA polymerase II 33 kDa polypeptide)
Gene: RPB3

Species: Schizosaccharomyces pombe 972h-

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.960

The method score is based on:

Property Details
Experiments 9642054, 10648788, 9325316, 15743411, 11839823, 11168400, 14534314, 15620689
Identification Methods far western blotting, pull down, affinity chromatography technology, biochemical, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_L~RNA_pol_Rpb1_2, RNA_pol_L~RNA_pol_Rpb1_3, RNA_pol_L~RNA_pol_Rpb1_4, RNA_pol_L~RNA_pol_Rpb1_5
Common GO terms GO:0000785 - chromatin
GO:0001055 - RNA polymerase II activity
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005665 - RNA polymerase II, core complex
and 3 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1752
Sp

1 297
+ Sc
+ Sc
+ Hs
+ Hs
+ Sc
+ Hv
+ Sc
+ Hs
+ Hs
+ At
+ At
+ Sc
+ At
+ At
+ Hv
+ Bt
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024