HitPredict

Interactor 1: RPB1 (P36594)
DNA-directed RNA polymerase II subunit rpb1 (RNA polymerase II subunit 1) (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase III largest subunit)
Gene: RPB1

Interactor 2: RPB11 (P87123)
DNA-directed RNA polymerase II subunit RPB11 (RNA polymerase II subunit B11) (DNA-directed RNA polymerase II 14.1 kDa polypeptide)
Gene: RPB11

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.909

The method score is based on:

Property Details
Experiments 9642054, 10648788, 9325316, 15743411, 14534314
Identification Methods far western blotting, pull down, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_L_2~RNA_pol_Rpb1_1, RNA_pol_L_2~RNA_pol_Rpb1_2, RNA_pol_L_2~RNA_pol_Rpb1_3
Common GO terms GO:0001055 - RNA polymerase II activity
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005665 - RNA polymerase II, core complex
GO:0005829 - cytosol
and 3 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1752
Sp

1 123
+ Sc
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ At
+ At
+ Sc
+ Bt
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024