HitPredict

Interactor 1: LONM (P36776)
Lon protease homolog, mitochondrial (EC 3.4.21.53) (LONHs) (Lon protease-like protein) (LONP) (Mitochondrial ATP-dependent protease Lon) (Serine protease 15)
Gene: LONP1

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	31478661, 31871319
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 959 Hs			1 191
+	Hs
		737485 LONM_HUMAN (1-959): 0: 1123: 100.00		RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17
+	Hs
		737298 LONM_HUMAN (1-959): 0: 1123: 100.00		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		737310 LONM_HUMAN (1-959): 0: 1123: 100.00		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		737290 LONM_HUMAN (1-959): 0: 1123: 100.00		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		545238 LONM_HUMAN (1-959): 0: 1123: 100.00		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		436180 LONM_HUMAN (1-959): 0: 1123: 100.00		RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41
+	Hs
		737287 LONM_HUMAN (1-959): 0: 1123: 100.00		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32
+	Hs
		737384 LONM_HUMAN (1-959): 0: 1123: 100.00		RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82
+	Hs
		874798 TERA_HUMAN (107-762): 3.63e-149: 463: 14.23		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		874753 TERA_HUMAN (107-762): 3.63e-149: 463: 14.23		CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00
+	Hs
		874762 TERA_HUMAN (107-762): 3.63e-149: 463: 14.23		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		545289 TERA_HUMAN (107-762): 3.63e-149: 463: 14.23		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		436226 TERA_HUMAN (107-762): 3.63e-149: 463: 14.23		RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41
+	Hs
		874748 TERA_HUMAN (107-762): 3.63e-149: 463: 14.23		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32
+	Sc
		580299 CDC48_YEAST (132-751): 9.63e-138: 434: 13.94		CDC42_YEAST (1-191): 2.69e-80: 238: 80.11
+	Sp
		963940 CDC48_SCHPO (132-748): 8.67e-136: 428: 12.69		CDC42_SCHPO (1-191): 2.1e-81: 241: 81.77
+	Hs
		925550 YMEL1_HUMAN (219-831): 3.25e-97: 325: 14.37		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31