Interactor 1: DPH5 (P32469)
Diphthine methyl ester synthase (EC 2.1.1.314) (Diphthamide biosynthesis methyltransferase)
Gene: DPH5

Interactor 2: DPH5 (P32469)
Diphthine methyl ester synthase (EC 2.1.1.314) (Diphthamide biosynthesis methyltransferase)
Gene: DPH5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.791

The method score is based on:

Property Details
Experiments 18467557, 22615397
Identification Methods protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains TP_methylase~TP_methylase
Common GO terms GO:0005737 - cytoplasm
GO:0017183 - protein histidyl modification to diphthamide
GO:0032259 - methylation
GO:0141133 - diphthine methyl ester synthase activity
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 300
Sc

1 300
+ Hs

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Last updated: 11Aug2025