HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: UBX2B (Q14CS0)
UBX domain-containing protein 2B (NSFL1 cofactor p37) (p97 cofactor p37)
Gene: UBXN2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26389662, 30344098, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 331
+	Hs
		905907 PP1A_HUMAN (1-323): 0: 579: 90.66		UBX2B_HUMAN (1-331): 9.93e-176: 491: 100.00
+	Hs
		906462 PP1B_HUMAN (1-322): 0: 560: 86.89		UBX2B_HUMAN (1-331): 9.93e-176: 491: 100.00
+	Hs
		738126 PP1G_HUMAN (1-323): 0: 603: 100.00		NSF1C_HUMAN (10-330): 4.14e-143: 410: 48.16
+	Hs
		737736 PP1G_HUMAN (1-323): 0: 603: 100.00		UBX2A_HUMAN (129-331): 1.13e-87: 265: 39.41
+	Hs
		905828 PP1A_HUMAN (1-323): 0: 579: 90.66		UBX2A_HUMAN (129-331): 1.13e-87: 265: 39.41
+	Sc
		696290 PP12_YEAST (3-304): 0: 550: 85.76		UBX1_YEAST (44-329): 2.3e-94: 288: 27.61
+	Hs
		906409 PP1B_HUMAN (1-322): 0: 560: 86.89		UBX2A_HUMAN (129-331): 1.13e-87: 265: 39.41
+	Sc
		643166 PPZ1_YEAST (7-300): 6.31e-148: 433: 67.46		UBX1_YEAST (44-329): 2.3e-94: 288: 27.61