HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: TOIP1 (Q5JTV8)
Torsin-1A-interacting protein 1 (Lamin-associated protein 1B) (LAP1B)
Gene: TOR1AIP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.670

Property	Details
Experiments	30344098, 23080069, 24116158
Identification Methods	affinity chromatography technology, two hybrid, far western blotting, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005521 - lamin binding GO:0005634 - nucleus
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 583
+	Rn
		926558 PP1G_RAT (1-323): 0: 602: 99.69		TOIP1_RAT (1-583): 0: 937: 70.07
+	Hs
		905949 PP1A_HUMAN (1-323): 0: 579: 90.66		TOIP1_HUMAN (1-583): 0: 954: 100.00
+	Rn
		906394 PP1A_RAT (1-323): 0: 579: 90.66		TOIP1_RAT (1-583): 0: 937: 70.07