HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: PPR3F (Q6ZSY5)
Protein phosphatase 1 regulatory subunit 3F (R3F)
Gene: PPP1R3F

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008157 - protein phosphatase 1 binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 799
+	Hs
		737831 PP1G_HUMAN (1-323): 0: 603: 100.00		PPR3A_HUMAN (13-349): 3.57e-73: 261: 24.35
+	Hs
		905933 PP1A_HUMAN (1-323): 0: 579: 90.66		PPR3A_HUMAN (13-349): 3.57e-73: 261: 24.35
+	Mm
		906352 PP1A_MOUSE (1-323): 0: 579: 90.36		PPR3A_MOUSE (16-348): 1.8e-67: 244: 25.15
+	Hs
		906477 PP1B_HUMAN (1-322): 0: 560: 86.89		PPR3A_HUMAN (13-349): 3.57e-73: 261: 24.35
+	Hs
		319090 PP1G_HUMAN (1-323): 0: 603: 100.00		PPR3D_HUMAN (2-295): 1.61e-63: 216: 23.65
+	Hs
		319093 PP1A_HUMAN (1-323): 0: 579: 90.66		PPR3D_HUMAN (2-295): 1.61e-63: 216: 23.65
+	Mm
		57204 PP1A_MOUSE (1-323): 0: 579: 90.36		A2AJW4_MOUSE (3-295): 8.69e-64: 216: 23.67
+	Hs
		81860 PP1A_HUMAN (1-323): 0: 579: 90.66		PP13G_HUMAN (30-283): 2.54e-50: 182: 25.28
+	Hs
		906138 PP1A_HUMAN (1-323): 0: 579: 90.66		PPR3E_HUMAN (5-303): 2.66e-46: 168: 25.08