HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: KCD20 (Q7Z5Y7)
BTB/POZ domain-containing protein KCTD20 (Potassium channel tetramerization domain containing 20)
Gene: KCTD20

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.695

Property	Details
Experiments	26186194, 28514442, 33961781, 23080069
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 419
+	Hs
		905990 PP1A_HUMAN (1-323): 0: 579: 90.66		KCD20_HUMAN (1-419): 0: 811: 100.00
+	Hs
		738008 PP1G_HUMAN (1-323): 0: 603: 100.00		BTBDA_HUMAN (109-405): 0: 517: 75.76
+	Hs
		906108 PP1A_HUMAN (1-323): 0: 579: 90.66		BTBDA_HUMAN (109-405): 0: 517: 75.76
+	Dm
		819206 PP11_DROME (5-323): 0: 569: 88.92		Q0E8K5_DROME (104-399): 0: 518: 59.80
+	Dm
		819245 PP11_DROME (5-323): 0: 569: 88.92		X2J8G3_DROME (104-399): 0: 512: 60.14
+	Dm
		524611 PP12_DROME (5-303): 0: 551: 93.31		Q0E8K5_DROME (104-399): 0: 518: 59.80
+	Dm
		524675 PP12_DROME (5-303): 0: 551: 93.31		X2J8G3_DROME (104-399): 0: 512: 60.14
+	Hs
		930974 PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08		BTBDA_HUMAN (109-405): 0: 517: 75.76
+	Ce
		821922 GLC7B_CAEEL (3-323): 0: 584: 89.63		Q21748_CAEEL (117-386): 1.54e-143: 419: 56.68
+	Ce
		821921 GLC7B_CAEEL (3-323): 0: 584: 89.63		Q21747_CAEEL (113-386): 2.87e-141: 417: 55.87