HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: SYNPO (Q8N3V7)
Synaptopodin
Gene: SYNPO

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 30344098
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043197 - dendritic spine
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 929
+	Hs
		906018 PP1A_HUMAN (1-323): 0: 579: 90.66		SYNPO_HUMAN (14-929): 5.01e-115: 376: 100.00
+	Hs
		906531 PP1B_HUMAN (1-322): 0: 560: 86.89		SYNPO_HUMAN (14-929): 5.01e-115: 376: 100.00
+	Mm
		906309 PP1A_MOUSE (1-323): 0: 579: 90.36		SYP2L_MOUSE (391-924): 9.69e-29: 126: 20.31
+	Hs
		905894 PP1A_HUMAN (1-323): 0: 579: 90.66		MDC1_HUMAN (24-925): 1.38e-27: 123: 12.28
+	Dm
		113980 PP1B_DROME (1-323): 0: 552: 82.48		M9PB30_DROME (235-926): 5.94e-28: 124: 11.57
+	Hs
		737992 PP1G_HUMAN (1-323): 0: 603: 100.00		CIC_HUMAN (71-922): 9.17e-10: 65.1: 8.24
+	Mm
		906349 PP1A_MOUSE (1-323): 0: 579: 90.36		TARA_MOUSE (10-914): 2.07e-13: 77: 9.09
+	Hs
		906093 PP1A_HUMAN (1-323): 0: 579: 90.66		CIC_HUMAN (71-922): 9.17e-10: 65.1: 8.24
+	Hs
		930846 PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08		MDC1_HUMAN (24-925): 1.38e-27: 123: 12.28
+	Hs
		915264 PP2AB_HUMAN (8-312): 2.02e-178: 497: 46.73		CIC_HUMAN (71-922): 9.17e-10: 65.1: 8.24