HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005739 - mitochondrion
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 530
+	Hs
		906054 PP1A_HUMAN (1-323): 0: 579: 90.66		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		906550 PP1B_HUMAN (1-322): 0: 560: 86.89		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369103 PP1G_HUMAN (1-323): 0: 603: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Mm
		587097 PP1G_MOUSE (1-323): 0: 602: 99.69		ESR1_MOUSE (9-529): 4.88e-134: 403: 43.72
+	Hs
		369309 PP1A_HUMAN (1-323): 0: 579: 90.66		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		915249 PP2AB_HUMAN (8-312): 2.02e-178: 497: 46.73		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369332 PP2AB_HUMAN (8-312): 2.02e-178: 497: 46.73		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369364 PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		320195 PP2AB_HUMAN (8-312): 2.02e-178: 497: 46.73		ERR2_HUMAN (69-499): 5.86e-109: 333: 31.57
+	Hs
		320201 PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08		ERR2_HUMAN (69-499): 5.86e-109: 333: 31.57
+	Hs
		437630 PP1A_HUMAN (1-323): 0: 579: 90.66		MCR_HUMAN (141-408): 5.92e-38: 150: 34.03
+	Hs
		487290 PP1A_HUMAN (1-323): 0: 579: 90.66		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487291 PP1B_HUMAN (1-322): 0: 560: 86.89		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487319 PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59