HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: IFIH1 (Q9BYX4)
Interferon-induced helicase C domain-containing protein 1 (EC 3.6.4.13) (Clinically amyopathic dermatomyositis autoantigen 140 kDa) (CADM-140 autoantigen) (Helicase with 2 CARD domains) (Helicard) (Interferon-induced with helicase C domain protein 1) (Melanoma differentiation-associated protein 5) (MDA-5) (Murabutide down-regulated protein) (RIG-I-like receptor 2) (RLR-2) (RNA helicase-DEAD box protein 116)
Gene: IFIH1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33727702
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 1025
+	Hs
		906114 PP1A_HUMAN (1-323): 0: 579: 90.66		IFIH1_HUMAN (1-1025): 0: 647: 99.12
+	Dm
		55481 PP1B_DROME (1-323): 0: 552: 82.48		DCR2_DROME (305-907): 1.08e-86: 308: 17.31
+	Dm
		55489 Q8T0U6_DROME (19-323): 0: 535: 83.39		DCR2_DROME (305-907): 1.08e-86: 308: 17.31
+	Hs
		133907 PP1G_HUMAN (1-323): 0: 603: 100.00		DDX3X_HUMAN (148-595): 7.66e-53: 199: 9.92
+	Hs
		571334 PP1G_HUMAN (1-323): 0: 603: 100.00		DDX5_HUMAN (216-596): 1.93e-49: 187: 11.54
+	Hs
		737955 PP1G_HUMAN (1-323): 0: 603: 100.00		DDX17_HUMAN (217-596): 1.62e-48: 187: 10.88
+	Mm
		906275 PP1A_MOUSE (1-323): 0: 579: 90.36		DDX3X_MOUSE (148-595): 8.61e-52: 196: 9.51
+	Hs
		133958 PP1B_HUMAN (1-322): 0: 560: 86.89		DDX3X_HUMAN (148-595): 7.66e-53: 199: 9.92
+	Sc
		696280 PP12_YEAST (3-304): 0: 550: 85.76		BRR2_YEAST (175-491): 2.97e-15: 83.4: 22.29