HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: PP12C (Q9BZL4)
Protein phosphatase 1 regulatory subunit 12C (Protein phosphatase 1 myosin-binding subunit of 85 kDa) (Protein phosphatase 1 myosin-binding subunit p85)
Gene: PPP1R12C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30344098
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 323 Hs			1 782
+	Hs
		906116 PP1A_HUMAN (1-323): 0: 579: 90.66		PP12C_HUMAN (1-782): 1.36e-154: 471: 100.00
+	Mm
		906252 PP1A_MOUSE (1-323): 0: 579: 90.36		PP12C_MOUSE (19-782): 1.24e-138: 429: 85.92
+	Hs
		737978 PP1G_HUMAN (1-323): 0: 603: 100.00		PP16A_HUMAN (13-478): 5.8e-85: 281: 29.56
+	Hs
		906079 PP1A_HUMAN (1-323): 0: 579: 90.66		PP16A_HUMAN (13-478): 5.8e-85: 281: 29.56
+	Hs
		738057 PP1G_HUMAN (1-323): 0: 603: 100.00		TANC2_HUMAN (4-720): 4.19e-69: 250: 16.47
+	Hs
		737999 PP1G_HUMAN (1-323): 0: 603: 100.00		PP16B_HUMAN (12-545): 6.28e-69: 239: 23.19
+	Hs
		906146 PP1A_HUMAN (1-323): 0: 579: 90.66		TANC2_HUMAN (4-720): 4.19e-69: 250: 16.47
+	Hs
		906099 PP1A_HUMAN (1-323): 0: 579: 90.66		PP16B_HUMAN (12-545): 6.28e-69: 239: 23.19
+	Hs
		225129 PP1G_HUMAN (1-323): 0: 603: 100.00		MYPT2_HUMAN (353-782): 4.07e-27: 120: 21.69
+	Hs
		3260 PP1B_HUMAN (1-322): 0: 560: 86.89		A0A0S2Z4Q8_HUMAN (12-191): 1.32e-41: 152: 49.74
+	Hs
		161322 PP1G_HUMAN (1-323): 0: 603: 100.00		MYPT1_HUMAN (542-782): 1.47e-22: 105: 33.61
+	Mm
		906293 PP1A_MOUSE (1-323): 0: 579: 90.36		MYPT2_MOUSE (298-782): 1.34e-28: 125: 23.16
+	Hs
		737925 PP1G_HUMAN (1-323): 0: 603: 100.00		ANR42_HUMAN (187-357): 5.42e-22: 100: 20.00
+	Mm
		926555 PP1G_MOUSE (1-323): 0: 602: 99.69		MYPT1_MOUSE (542-782): 3.39e-21: 101: 32.78
+	Hs
		225132 PP1A_HUMAN (1-323): 0: 579: 90.66		MYPT2_HUMAN (353-782): 4.07e-27: 120: 21.69
+	Hs
		905838 PP1A_HUMAN (1-323): 0: 579: 90.66		ANK2_HUMAN (192-510): 1.07e-25: 116: 13.86
+	Hs
		161347 PP1A_HUMAN (1-323): 0: 579: 90.66		MYPT1_HUMAN (542-782): 1.47e-22: 105: 33.61
+	Mm
		906366 PP1A_MOUSE (1-323): 0: 579: 90.36		MYPT1_MOUSE (542-782): 3.39e-21: 101: 32.78
+	Gg
		907234 PP1B_CHICK (1-322): 0: 560: 86.89		MYPT1_CHICK (10-232): 1.66e-24: 112: 16.54
+	Hs
		906000 PP1A_HUMAN (1-323): 0: 579: 90.66		PPR27_HUMAN (223-309): 1.62e-09: 59.3: 40.23