HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: LIMA1 (Q9UHB6)
LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm)
Gene: LIMA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 30344098
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0032154 - cleavage furrow GO:0046872 - metal ion binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 759
+	Hs
		906188 PP1A_HUMAN (1-323): 0: 579: 90.66		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		906624 PP1B_HUMAN (1-322): 0: 560: 86.89		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		906527 PP1B_HUMAN (1-322): 0: 560: 86.89		MILK2_HUMAN (295-569): 1.42e-37: 153: 22.95
+	Hs
		150548 PP1B_HUMAN (1-322): 0: 560: 86.89		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		200169 PP1A_HUMAN (1-323): 0: 579: 90.66		TGFI1_HUMAN (263-447): 1.47e-16: 85: 15.64
+	Dm
		1196945 Q8T0U6_DROME (19-323): 0: 535: 83.39		MICAL_DROME (371-515): 6.96e-12: 71.8: 24.83
+	Hs
		823368 PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08		PAXI_HUMAN (268-446): 5.9e-14: 77.3: 14.53