HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: WBP11 (Q9Y2W2)
WW domain-binding protein 11 (WBP-11) (Npw38-binding protein) (NpwBP) (SH3 domain-binding protein SNP70) (Splicing factor that interacts with PQBP-1 and PP1)
Gene: WBP11

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.734

Property	Details
Experiments	26186194, 27880917, 28514442, 30344098, 33961781, 23080069
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 641
+	Mm
		926553 PP1G_MOUSE (1-323): 0: 602: 99.69		WBP11_MOUSE (1-641): 1.75e-82: 274: 95.16
+	Mm
		906344 PP1A_MOUSE (1-323): 0: 579: 90.36		WBP11_MOUSE (1-641): 1.75e-82: 274: 95.16
+	Hs
		906210 PP1A_HUMAN (1-323): 0: 579: 90.66		WBP11_HUMAN (1-641): 2.71e-82: 273: 100.00
+	Hs
		906643 PP1B_HUMAN (1-322): 0: 560: 86.89		WBP11_HUMAN (1-641): 2.71e-82: 273: 100.00
+	Hs
		90115 PP1A_HUMAN (1-323): 0: 579: 90.66		D6REX3_HUMAN (295-623): 9.1e-18: 89.8: 13.37
+	Dm
		113980 PP1B_DROME (1-323): 0: 552: 82.48		M9PB30_DROME (162-626): 8.11e-09: 61.3: 9.68