HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: SNCAP (Q9Y6H5)
Synphilin-1 (Sph1) (Alpha-synuclein-interacting protein)
Gene: SNCAIP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.698

Property	Details
Experiments	24902662, 26186194, 28514442, 33961781
Identification Methods	two hybrid, far western blotting, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 919
+	Hs
		906220 PP1A_HUMAN (1-323): 0: 579: 90.66		SNCAP_HUMAN (1-919): 0: 553: 100.00
+	Hs
		905838 PP1A_HUMAN (1-323): 0: 579: 90.66		ANK2_HUMAN (193-789): 6.03e-89: 313: 12.54
+	Hs
		906005 PP1A_HUMAN (1-323): 0: 579: 90.66		MIB1_HUMAN (309-736): 2.35e-48: 188: 11.82
+	Hs
		737925 PP1G_HUMAN (1-323): 0: 603: 100.00		ANR42_HUMAN (274-578): 1.34e-30: 126: 18.75
+	Hs
		49893 PP1G_HUMAN (1-323): 0: 603: 100.00		A1DRY3_HUMAN (274-557): 2.57e-27: 121: 18.12
+	Hs
		49894 PP1A_HUMAN (1-323): 0: 579: 90.66		A1DRY3_HUMAN (274-557): 2.57e-27: 121: 18.12
+	Hs
		738023 PP1G_HUMAN (1-323): 0: 603: 100.00		UACA_HUMAN (207-439): 3.69e-18: 92.3: 12.03
+	Mm
		906252 PP1A_MOUSE (1-323): 0: 579: 90.36		PP12C_MOUSE (245-453): 3.25e-21: 101: 14.74
+	Hs
		906584 PP1B_HUMAN (1-322): 0: 560: 86.89		UACA_HUMAN (207-439): 3.69e-18: 92.3: 12.03
+	Hs
		862021 PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08		DAPK1_HUMAN (212-439): 1.26e-36: 151: 17.60