Interactor 1: FLT3 (P36888)
Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)
Gene: FLT3

Interactor 2: FLT3 (P36888)
Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)
Gene: FLT3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.845

The method score is based on:

Property Details
Experiments 17851558, 21389326, 24525236
Identification Methods enzymatic study, pull down, protein kinase assay
Interaction Type direct interaction, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains ig~ig, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr
Common GO terms GO:0001776 - leukocyte homeostasis
GO:0002318 - myeloid progenitor cell differentiation
GO:0002328 - pro-B cell differentiation
GO:0004713 - protein tyrosine kinase activity
GO:0004714 - transmembrane receptor protein tyrosine kinase activity
and 31 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 993
Hs

1 993
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Last updated: 15 Jul 2024