HitPredict

Interactor 1: FLT3 (P36888)
Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)
Gene: FLT3

Interactor 2: RACK1 (P63244)
Small ribosomal subunit protein RACK1 (Cell proliferation-inducing gene 21 protein) (Guanine nucleotide-binding protein subunit beta-2-like 1) (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Human lung cancer oncogene 7 protein) (HLC-7) (Receptor for activated C kinase) (Receptor of activated protein C kinase 1) [Cleaved into: Small ribosomal subunit protein RACK1, N-terminally processed (Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed) (Receptor of activated protein C kinase 1, N-terminally processed)]
Gene: RACK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 993 Hs			1 317
+	Hs
		738171 FLT3_HUMAN (1-993): 0: 844: 97.89		LIS1_HUMAN (144-316): 6.1e-46: 162: 23.43
+	Hs
		572616 VGFR1_HUMAN (74-537): 1.47e-36: 152: 14.31		RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00
+	Hs
		169170 MUSK_HUMAN (6-354): 1.85e-28: 125: 11.62		RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00
+	Hs
		572595 VGFR1_HUMAN (74-537): 1.47e-36: 152: 14.31		LIS1_HUMAN (144-316): 6.1e-46: 162: 23.43
+	Hs
		609202 FGFR3_HUMAN (20-260): 5.2e-21: 101: 9.09		LIS1_HUMAN (144-316): 6.1e-46: 162: 23.43