HitPredict

Interactor 1: FLT3 (P36888)
Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)
Gene: FLT3

Interactor 2: SMC1A (Q14683)
Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Sb1.8)
Gene: SMC1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 993 Hs			1 1233
+	Hs
		311491 FLT3_HUMAN (1-993): 0: 844: 97.89		SMC2_HUMAN (3-1214): 1.55e-77: 281: 17.57
+	Hs
		738293 FLT3_HUMAN (1-993): 0: 844: 97.89		SMC3_HUMAN (3-1229): 1.52e-70: 260: 16.00
+	Hs
		572635 VGFR1_HUMAN (74-537): 1.47e-36: 152: 14.31		SMC1A_HUMAN (1-1233): 1.94e-128: 427: 100.00
+	Hs
		729279 VGFR3_HUMAN (70-533): 8.45e-27: 120: 14.15		SMC1A_HUMAN (1-1233): 1.94e-128: 427: 100.00
+	Hs
		609288 FGFR3_HUMAN (20-260): 5.2e-21: 101: 9.09		SMC1A_HUMAN (1-1233): 1.94e-128: 427: 100.00
+	Hs
		311473 VGFR1_HUMAN (74-537): 1.47e-36: 152: 14.31		SMC2_HUMAN (3-1214): 1.55e-77: 281: 17.57
+	Hs
		311490 VGFR3_HUMAN (70-533): 8.45e-27: 120: 14.15		SMC2_HUMAN (3-1214): 1.55e-77: 281: 17.57
+	Hs
		311465 FGFR1_HUMAN (6-360): 2.83e-24: 111: 10.90		SMC2_HUMAN (3-1214): 1.55e-77: 281: 17.57
+	Hs
		311477 FGFR3_HUMAN (20-260): 5.2e-21: 101: 9.09		SMC2_HUMAN (3-1214): 1.55e-77: 281: 17.57
+	Hs
		729386 VGFR3_HUMAN (70-533): 8.45e-27: 120: 14.15		SMC3_HUMAN (3-1229): 1.52e-70: 260: 16.00
+	Hs
		609617 FGFR3_HUMAN (20-260): 5.2e-21: 101: 9.09		SMC3_HUMAN (3-1229): 1.52e-70: 260: 16.00