HitPredict

Interactor 1: BMR1A (P36894)
Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)
Gene: BMPR1A

Interactor 2: FKB1A (P62942)
Peptidyl-prolyl cis-trans isomerase FKBP1A (PPIase FKBP1A) (EC 5.2.1.8) (12 kDa FK506-binding protein) (12 kDa FKBP) (FKBP-12) (Calstabin-1) (FK506-binding protein 1A) (FKBP-1A) (Immunophilin FKBP12) (Rotamase)
Gene: FKBP1A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	9663660
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	FKBP_C~Pkinase, FKBP_C~TGF_beta_GS
Common GO terms	GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 532 Hs			1 108
+	Hs
		738328 BMR1A_HUMAN (1-532): 5.05e-164: 477: 100.00		FKB1B_HUMAN (1-108): 2.61e-52: 161: 83.33
+	Hs
		738520 TGFR1_HUMAN (26-532): 9.84e-139: 412: 49.22		FKB1A_HUMAN (1-108): 2e-54: 166: 100.00
+	Hs
		738525 TGFR1_HUMAN (26-532): 9.84e-139: 412: 49.22		FKB1B_HUMAN (1-108): 2.61e-52: 161: 83.33
+	Hs
		923822 ACVR1_HUMAN (52-529): 7.23e-135: 402: 48.86		FKB1A_HUMAN (1-108): 2e-54: 166: 100.00
+	Hs
		738439 ACV1B_HUMAN (47-532): 1.83e-128: 385: 49.19		FKB1A_HUMAN (1-108): 2e-54: 166: 100.00
+	Hs
		739522 ACVL1_HUMAN (57-531): 4.4e-128: 385: 45.72		FKB1A_HUMAN (1-108): 2e-54: 166: 100.00
+	Hs
		1034871 AMHR2_HUMAN (235-529): 2.38e-39: 152: 33.23		FKBP5_HUMAN (2-108): 3.73e-15: 71.3: 28.44