HitPredict

Interactor 1: BMR1A (P36894)
Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)
Gene: BMPR1A

Interactor 2: BMPR2 (Q13873)
Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)
Gene: BMPR2

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 7791754, 10712517
Identification Methods affinity chromatography technology, coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Activin_recp~Activin_recp, Pkinase~Pkinase, Pkinase~TGF_beta_GS
Common GO terms GO:0001649 - osteoblast differentiation
GO:0001707 - mesoderm formation
GO:0003151 - outflow tract morphogenesis
GO:0003183 - mitral valve morphogenesis
GO:0003186 - tricuspid valve morphogenesis
and 19 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 532
Hs

1 1038
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024