Interactor 1: BMR1A (P36894)
Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)
Gene: BMPR1A

Interactor 2: TBK1 (Q9UHD2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)
Gene: TBK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 27684187
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase, Pkinase~TBK1_CCD1, Pkinase~TBK1_ULD, Pkinase~TGF_beta_GS
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0010629 - negative regulation of gene expression
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 532
Hs

1 729
+ Mm
+ Mm
+ Mm
+ Mm
+ At
+ At
+ At
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024