HitPredict

Interactor 1: ACV1B (P36896)
Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2)
Gene: ACVR1B

Interactor 2: XIAP (P98170)
E3 ubiquitin-protein ligase XIAP (EC 2.3.2.27) (Baculoviral IAP repeat-containing protein 4) (IAP-like protein) (ILP) (hILP) (Inhibitor of apoptosis protein 3) (IAP-3) (hIAP-3) (hIAP3) (RING-type E3 ubiquitin transferase XIAP) (X-linked inhibitor of apoptosis protein) (X-linked IAP)
Gene: XIAP

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	11356828
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0046872 - metal ion binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 505 Hs			1 497
+	Hs
		122287 BMR1B_HUMAN (19-505): 8.25e-143: 421: 49.80		XIAP_HUMAN (1-497): 0: 569: 100.00
+	Hs
		738529 TGFR1_HUMAN (33-505): 3.15e-139: 412: 70.17		XIAP_HUMAN (1-497): 0: 569: 100.00
+	Mm
		1141988 TGFR1_MOUSE (27-505): 3.64e-141: 417: 70.12		XIAP_MOUSE (1-497): 0: 544: 88.73
+	Hs
		957700 BMPR2_HUMAN (1-497): 1.81e-95: 313: 28.68		XIAP_HUMAN (1-497): 0: 569: 100.00
+	Dm
		1097073 Q24326_DROME (19-500): 8.49e-124: 375: 43.56		DIAP2_DROME (14-98): 7.09e-22: 100: 34.12
+	Dm
		1097048 Q24326_DROME (19-500): 8.49e-124: 375: 43.56		DIAP1_DROME (243-424): 7.45e-17: 84.6: 20.21
+	Hs
		1046375 BMPR2_HUMAN (1-497): 1.81e-95: 313: 28.68		MIB1_HUMAN (311-492): 5.04e-16: 83.1: 13.68
+	At
		186964 BRI1_ARATH (4-79): 3.15e-09: 61.7: 12.99		Q8LBF1_ARATH (408-495): 1.29e-23: 105: 29.21