HitPredict

Interactor 1: TGFR1 (P36897)
TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)
Gene: TGFBR1

Interactor 2: KCNKI (Q7Z418)
Potassium channel subfamily K member 18 (TWIK-related individual potassium channel) (TWIK-related spinal cord potassium channel)
Gene: KCNK18

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15761153
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 503 Hs			1 384
+	Hs
		981124 ACVR1_HUMAN (10-500): 8.17e-136: 403: 49.30		KCNKI_HUMAN (1-384): 1.4e-131: 384: 100.00
+	Hs
		738366 BMR1A_HUMAN (21-503): 4.05e-134: 400: 50.92		KCNKI_HUMAN (1-384): 1.4e-131: 384: 100.00
+	Hs
		740000 TGFR2_HUMAN (38-497): 1.43e-118: 361: 31.94		KCNKI_HUMAN (1-384): 1.4e-131: 384: 100.00
+	Hs
		646041 AVR2A_HUMAN (53-497): 1.95e-107: 331: 30.20		KCNKI_HUMAN (1-384): 1.4e-131: 384: 100.00
+	Hs
		1044919 AVR2B_HUMAN (53-498): 2.08e-105: 325: 30.50		KCNT2_HUMAN (283-368): 2.85e-19: 91.8: 24.72