HitPredict

Interactor 1: TGFR1 (P36897)
TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)
Gene: TGFBR1

Interactor 2: CLC2B (Q92478)
C-type lectin domain family 2 member B (Activation-induced C-type lectin) (C-type lectin superfamily member 2) (IFN-alpha-2b-inducing-related protein 1)
Gene: CLEC2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 503 Hs			1 149
+	Hs
		738590 TGFR1_HUMAN (1-503): 6.66e-149: 437: 100.00		CLC4E_HUMAN (28-146): 4.09e-37: 128: 29.63
+	Hs
		738591 TGFR1_HUMAN (1-503): 6.66e-149: 437: 100.00		CLC4A_HUMAN (16-147): 7.74e-35: 122: 23.13
+	Hs
		738539 TGFR1_HUMAN (1-503): 6.66e-149: 437: 100.00		KLRD1_HUMAN (25-148): 9.94e-33: 115: 26.72
+	Hs
		738535 TGFR1_HUMAN (1-503): 6.66e-149: 437: 100.00		KLRB1_HUMAN (35-148): 5.48e-30: 110: 27.27
+	Hs
		740037 TGFR2_HUMAN (38-497): 1.43e-118: 361: 31.94		KLRG1_HUMAN (10-146): 5.86e-37: 126: 27.78