Interactor 1: TNR3 (P36941)
Tumor necrosis factor receptor superfamily member 3 (Lymphotoxin-beta receptor) (Tumor necrosis factor C receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor receptor type III) (TNF-RIII) (TNFR-III)
Gene: LTBR

Interactor 2: TNFC (Q06643)
Lymphotoxin-beta (LT-beta) (Tumor necrosis factor C) (TNF-C) (Tumor necrosis factor ligand superfamily member 3)
Gene: LTB

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 8171323
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains TNF~TNFR_c6
Common GO terms GO:0005886 - plasma membrane
GO:0006955 - immune response
GO:0007165 - signal transduction
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:2001238 - positive regulation of extrinsic apoptotic signaling pathway
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 435
Hs

1 244
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024