HitPredict

Interactor 1: TNR3 (P36941)
Tumor necrosis factor receptor superfamily member 3 (Lymphotoxin-beta receptor) (Tumor necrosis factor C receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor receptor type III) (TNF-RIII) (TNFR-III)
Gene: LTBR

Interactor 2: VAPA (Q9P0L0)
Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A) (33 kDa VAMP-associated protein) (VAP-33)
Gene: VAPA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 435 Hs			1 249
+	Hs
		310530 TNR3_HUMAN (1-435): 8.16e-134: 393: 100.00		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Mm
		626883 TNR1A_MOUSE (36-339): 2.63e-54: 188: 22.83		VAPA_MOUSE (1-249): 2.59e-99: 291: 97.19
+	Hs
		433197 LAMB1_HUMAN (33-191): 2.4e-10: 64.9: 15.98		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		502880 LAMC1_HUMAN (30-145): 6.4e-09: 60.3: 15.22		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00