HitPredict

Interactor 1: RPB9 (P36954)
DNA-directed RNA polymerase II subunit RPB9 (RNA polymerase II subunit B9) (DNA-directed RNA polymerase II subunit I) (RNA polymerase II 14.5 kDa subunit) (RPB14.5)
Gene: POLR2I

Interactor 2: RPAB5 (P62875)
DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (DNA-directed RNA polymerase III subunit L) (RNA polymerase II 7.6 kDa subunit) (RPB7.6) (RPB10 homolog)
Gene: POLR2L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	24981860, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003899 - DNA-directed 5'-3' RNA polymerase activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005665 - RNA polymerase II, core complex GO:0006366 - transcription by RNA polymerase II and 1 others more... GO:0008270 - zinc ion binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 125 Hs			1 67
+	Hs
		921195 RPC10_HUMAN (14-125): 6.76e-35: 117: 26.79		RPAB5_HUMAN (1-67): 3.73e-35: 114: 100.00
+	Sc
		604656 RPB9_YEAST (11-124): 3.78e-38: 126: 43.86		RPAB5_YEAST (1-67): 1.8e-30: 103: 72.06
+	Sc
		604713 RPC10_YEAST (14-125): 3.41e-32: 111: 27.43		RPAB5_YEAST (1-67): 1.8e-30: 103: 72.06
+	Hs
		921185 RPA12_HUMAN (12-125): 2.72e-23: 89: 16.67		RPAB5_HUMAN (1-67): 3.73e-35: 114: 100.00
+	Sc
		604663 RPA12_YEAST (11-124): 1.49e-22: 87.1: 15.70		RPAB5_YEAST (1-67): 1.8e-30: 103: 72.06