HitPredict

Interactor 1: SRBP1 (P36956)
Sterol regulatory element-binding protein 1 (SREBP-1) (Class D basic helix-loop-helix protein 1) (bHLHd1) (Sterol regulatory element-binding transcription factor 1) [Cleaved into: Processed sterol regulatory element-binding protein 1 (Transcription factor SREBF1)]
Gene: SREBF1

Interactor 2: H4 (P62805)
Histone H4
Gene: H4C1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30804502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1147 Hs			1 103
+	Hs
		917953 MLXIP_HUMAN (26-417): 5e-35: 147: 15.10		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		252913 MITF_HUMAN (36-443): 6.88e-30: 127: 17.06		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Mm
		918249 TFE3_MOUSE (134-438): 8.24e-28: 121: 19.30		H4_MOUSE (1-103): 1.38e-48: 151: 100.00
+	Hs
		585646 TFE3_HUMAN (134-438): 2.03e-27: 120: 19.62		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		585112 TFEB_HUMAN (136-462): 1.05e-16: 86.5: 16.95		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917972 MLXPL_HUMAN (25-419): 4.11e-15: 82.7: 14.97		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		918062 CHD7_HUMAN (52-533): 8.09e-14: 78.9: 9.32		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		867089 SC24C_HUMAN (221-542): 2e-12: 73.8: 8.95		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917476 SRCAP_HUMAN (1-547): 9.18e-11: 68.8: 11.23		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917684 CBP_HUMAN (18-407): 2.51e-10: 67.3: 12.37		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917621 KMT2C_HUMAN (3-442): 7.45e-09: 62.7: 10.06		H4_HUMAN (1-103): 1.38e-48: 151: 100.00