HitPredict

Interactor 1: ODO2 (P36957)
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2) (OGDC-E2) (Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex) (E2K)
Gene: DLST

Interactor 2: M2OM (Q02978)
Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP) (alpha-oxoglutarate carrier) (Solute carrier family 25 member 11) (SLC25A11)
Gene: SLC25A11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005739 - mitochondrion
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 453 Hs			1 314
+	Hs
		739340 ODO2_HUMAN (1-453): 0: 538: 100.00		S2513_HUMAN (3-122): 5.08e-23: 101: 20.83
+	Hs
		274502 ODO2_HUMAN (1-453): 0: 538: 100.00		S2512_HUMAN (3-122): 4.43e-20: 92.6: 19.17
+	Hs
		518269 ODO2_HUMAN (1-453): 0: 538: 100.00		ADT3_HUMAN (7-109): 3.4e-11: 64.8: 21.15
+	Hs
		397295 ODO2_HUMAN (1-453): 0: 538: 100.00		ADT2_HUMAN (7-108): 1.65e-10: 62.9: 18.45
+	Mm
		851108 ODO2_MOUSE (1-453): 0: 529: 91.19		ADT2_MOUSE (7-108): 7.33e-11: 63.7: 18.45