Interactor 1: GMPR1 (P36959)
GMP reductase 1 (GMPR 1) (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 1) (Guanosine monophosphate reductase 1)
Gene: GMPR

Interactor 2: GMPR2 (Q9P2T1)
GMP reductase 2 (GMPR 2) (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 2) (Guanosine monophosphate reductase 2)
Gene: GMPR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains IMPDH~IMPDH
Common GO terms GO:0003920 - GMP reductase activity
GO:0005829 - cytosol
GO:0006144 - purine nucleobase metabolic process
GO:0046872 - metal ion binding
GO:1902560 - GMP reductase complex
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 345
Hs

1 348
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Last updated: 15 Jul 2024