HitPredict

Interactor 1: ACVL1 (P37023)
Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I)
Gene: ACVRL1

Interactor 2: BAMBI (Q13145)
BMP and activin membrane-bound inhibitor homolog (Non-metastatic gene A protein) (Putative transmembrane protein NMA)
Gene: BAMBI

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	19758997
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007179 - transforming growth factor beta receptor signaling pathway GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 503 Hs			1 260
+	Hs
		122288 BMR1B_HUMAN (21-497): 5.19e-137: 406: 45.29		BAMBI_HUMAN (1-260): 6.66e-180: 496: 100.00
+	Hs
		738339 BMR1A_HUMAN (30-497): 4.2e-134: 400: 45.91		BAMBI_HUMAN (1-260): 6.66e-180: 496: 100.00
+	Hs
		738537 TGFR1_HUMAN (33-495): 3.97e-131: 391: 48.63		BAMBI_HUMAN (1-260): 6.66e-180: 496: 100.00
+	Hs
		981115 ACVR1_HUMAN (10-501): 2.48e-130: 390: 59.00		BAMBI_HUMAN (1-260): 6.66e-180: 496: 100.00
+	Hs
		738445 ACV1B_HUMAN (14-493): 1.88e-123: 371: 47.86		BAMBI_HUMAN (1-260): 6.66e-180: 496: 100.00