HitPredict

Interactor 1: SCNNG (P37091)
Amiloride-sensitive sodium channel subunit gamma (Epithelial Na(+) channel subunit gamma) (Gamma-ENaC) (Gamma-NaCH) (Nonvoltage-gated sodium channel 1 subunit gamma) (SCNEG)
Gene: Scnn1g

Interactor 2: Q4V8H7 (Q4V8H7)
E3 ubiquitin-protein ligase (EC 2.3.2.26)
Gene: Wwp1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	14556380
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 650 Rn			1 918
+	Hs
		845991 SCNNG_HUMAN (1-650): 0: 768: 86.62		NED4L_HUMAN (1-915): 0: 805: 33.67
+	Hs
		739608 SCNNA_HUMAN (24-631): 0: 583: 33.33		WWP1_HUMAN (1-918): 0: 941: 90.02
+	Hs
		125257 SCNNG_HUMAN (1-650): 0: 768: 86.62		WWP2_HUMAN (1-918): 0: 732: 47.57
+	Hs
		845977 SCNNB_HUMAN (7-634): 0: 599: 35.89		ITCH_HUMAN (1-918): 0: 890: 56.93
+	Mm
		93286 SCNNG_MOUSE (1-650): 0: 784: 96.49		E9PXB7_MOUSE (99-915): 0: 697: 36.00
+	Hs
		739603 SCNNA_HUMAN (24-631): 0: 583: 33.33		ITCH_HUMAN (1-918): 0: 890: 56.93
+	Hs
		808050 SCNNG_HUMAN (1-650): 0: 768: 86.62		NEDD4_HUMAN (89-915): 0: 687: 34.65
+	Hs
		845978 SCNNB_HUMAN (7-634): 0: 599: 35.89		NED4L_HUMAN (1-915): 0: 805: 33.67
+	Hs
		739604 SCNNA_HUMAN (24-631): 0: 583: 33.33		NED4L_HUMAN (1-915): 0: 805: 33.67
+	Hs
		125256 SCNNB_HUMAN (7-634): 0: 599: 35.89		WWP2_HUMAN (1-918): 0: 732: 47.57
+	Hs
		125197 SCNNA_HUMAN (24-631): 0: 583: 33.33		WWP2_HUMAN (1-918): 0: 732: 47.57
+	Hs
		808049 SCNNB_HUMAN (7-634): 0: 599: 35.89		NEDD4_HUMAN (89-915): 0: 687: 34.65
+	Mm
		93285 SCNNB_MOUSE (17-634): 0: 579: 35.99		E9PXB7_MOUSE (99-915): 0: 697: 36.00
+	Hs
		739582 SCNNA_HUMAN (24-631): 0: 583: 33.33		NEDD4_HUMAN (89-915): 0: 687: 34.65
+	Hs
		739597 SCNNA_HUMAN (24-631): 0: 583: 33.33		HUWE1_HUMAN (131-917): 6.29e-176: 568: 24.56
+	Rn
		739631 SCNNG_RAT (1-650): 0: 791: 100.00		NEDD4_RAT (10-424): 1.62e-55: 209: 21.09
+	Mm
		808383 SCNNG_MOUSE (1-650): 0: 784: 96.49		NEDD4_MOUSE (3-424): 3.29e-53: 202: 21.08
+	Rn
		739628 SCNNB_RAT (17-634): 0: 592: 36.15		NEDD4_RAT (10-424): 1.62e-55: 209: 21.09
+	Hs
		845975 SCNNB_HUMAN (7-634): 0: 599: 35.89		HECW1_HUMAN (140-515): 3.34e-10: 66.5: 19.84
+	Hs
		739596 SCNNA_HUMAN (24-631): 0: 583: 33.33		HECW1_HUMAN (140-515): 3.34e-10: 66.5: 19.84