HitPredict

Interactor 1: TGFR2 (P37173)
TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II)
Gene: TGFBR2

Interactor 2: TGFB2 (P61812)
Transforming growth factor beta-2 proprotein (Cetermin) (Glioblastoma-derived T-cell suppressor factor) (G-TSF) [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-2 (TGF-beta-2)]
Gene: TGFB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 11157754
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains TGF_beta~ecTbetaR2
Common GO terms GO:0001837 - epithelial to mesenchymal transition
GO:0003148 - outflow tract septum morphogenesis
GO:0003149 - membranous septum morphogenesis
GO:0003181 - atrioventricular valve morphogenesis
GO:0003274 - endocardial cushion fusion
and 14 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024