HitPredict

Interactor 1: DIS3 (P37202)
Exosome complex exonuclease dis3 (EC 3.1.13.-) (EC 3.1.26.-) (Chromosome disjunction protein 3) (Mitotic control protein dis3) (Ribosomal RNA-processing protein 44)
Gene: DIS3

Interactor 2: RRP6 (Q10146)
Exosome complex exonuclease rrp6 (EC 3.1.13.-) (Ribosomal RNA-processing protein 6)
Gene: RRP6

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.640

The method score is based on:

Property Details
Experiments 30321377, 31064814, 23503588
Identification Methods affinity chromatography technology, proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000176 - nuclear exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000785 - chromatin
and 10 others

more...
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 970
Sp

1 777
+ Hs
+ Hs
+ Sc
+ Dm
+ Pf

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024