HitPredict

Interactor 1: PPARG (P37231)
Peroxisome proliferator-activated receptor gamma (PPAR-gamma) (Nuclear receptor subfamily 1 group C member 3)
Gene: PPARG

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26260846
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction GO:0032869 - cellular response to insulin stimulus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 505 Hs			1 247
+	Hs
		683175 PPARG_HUMAN (1-505): 2.47e-165: 479: 100.00		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		369315 ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		369308 ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Dm
		709148 ECR_DROME (108-501): 2.18e-101: 325: 25.82		1433E_DROME (1-243): 1.58e-140: 396: 63.37
+	Mm
		509296 RARA_MOUSE (45-503): 3.03e-102: 316: 25.22		1433G_MOUSE (1-247): 3.15e-139: 392: 100.00
+	Hs
		909878 ESR2_HUMAN (23-502): 1.79e-98: 308: 18.70		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		904942 ESR2_HUMAN (23-502): 1.79e-98: 308: 18.70		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		377266 GCR_HUMAN (18-503): 1.99e-98: 315: 17.85		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		369070 ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		369354 ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		369023 ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		369071 ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Mm
		509305 RARA_MOUSE (45-503): 3.03e-102: 316: 25.22		1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59
+	Mm
		509343 RARA_MOUSE (45-503): 3.03e-102: 316: 25.22		1433B_MOUSE (2-247): 8.57e-109: 315: 75.81
+	Hs
		320172 ERR2_HUMAN (25-502): 1.06e-104: 321: 19.14		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		683595 ESR2_HUMAN (23-502): 1.79e-98: 308: 18.70		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		927369 ESR2_HUMAN (23-502): 1.79e-98: 308: 18.70		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		647162 ESR2_HUMAN (23-502): 1.79e-98: 308: 18.70		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		377131 GCR_HUMAN (18-503): 1.99e-98: 315: 17.85		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Hs
		684247 ESR2_HUMAN (23-502): 1.79e-98: 308: 18.70		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16